Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps2-13-06 | Surgery | ETA2023

Prospective implementation of thyroid lobectomy recommendations and thyrospec molecular testing for bethesda III and IV nodules and impact on surgery

Yeo Caitlin , Wu Jiahui , Stewardson Paul , Eszlinger Markus , Paschke Ralf

Objectives: In May 2016, the local thyroid cancer tumor group proposed and adopted specific thyroid lobectomy recommendations based on the 2015 ATA guidelines. ThyroSPEC molecular testing was introduced for all Bethesda III and IV lesions in August 2020. The goal of this study was to evaluate the implementation of the ATA lobectomy guidelines and the introduction of ThyroSPEC molecular testing on rates of upfront total thyroidectomy (TTx), diagnostic lobectomy for Bethesda I-I...

ea0092op-12-01 | Oral Session 12: Emerging Insights into Thyroid Cancer Genetics | ETA2023

Prospective evaluation of thyrospec molecular testing of indeterminate thyroid nodule cytologies following diagnostic pathway optimization

Stewardson Paul , Eszlinger Markus , Wu Jiahui , Khalil Moosa , J Demetrick Douglas , Cheung Winson , Box Adrian , Paschke Ralf

Objectives: Molecular diagnostic tests for indeterminate thyroid nodules (ITNs) are marketed based on negative predictive value (NPV) and benign call rate. Arguments that unnecessary surgeries are avoided based on NPV/BCR incorrectly assume that all ITNs would undergo diagnostic surgery in the absence of molecular testing. In our practice with centralized triage and cytopathology the resection and malignancy rate, respectively, were 21% and 26% for AUS/FLUS and 56% and 43% for...